Bronchodilators and bronchial hyperresponsiveness.

Do bronchodilators adversely affect the prognosis of bronchial hyperresponsiveness?

Do bronchodilators adversely affect the prognosis of bronchial hyperresponsiveness? The possible adverse effects of bronchodilators on the prognosis of bronchial hyperresponsiveness (BHR) is currently a topical subject. Studies on this subject are, however, scarce. Many studies have dealt with the immediate or short term effect of bronchodilators on BHR, but to study the effects of these drugs ...

Bronchodilators and bronchial

In a recent editorial (May 1993; 48: 470-3) Drs van Schayck and van Herwaarden present a surprisingly ambivalent account of the effects of agonist treatment on airway responsiveness. Their conclusion that agonists have an unimportant effect on responsiveness appears to be based on recent analyses of data from their own study.' However, a thorough review of the studies discussed by van Schayck a...

Allergen-induced Bronchial Hyperresponsiveness

Bradykinin (BK) is a peptide mediator generated at sites of inflammation and its effects are mediated through constitutively expressed B 2 receptor or through induction of B 1 receptors. We examined the role of these receptors in bronchial hyperresponsiveness (BHR). Brown-Norway rats sensitized with ovalbumin (OA) and Al(OH) 3 intraperitoneally, were exposed 3 wk later to either saline or OA ae...

Bronchial Hyperresponsiveness in Asthma*

Measurement ofnonspecific bronchial hyperresponsiveness remains largely a research tool in asthma, and its usefulness in the assessment and management of asthma is poorly defined. We StUdied the relationship of bronchial hyperresponsiveness to the clinical severity of asthma in 54 asthmatic subjects. In order to find out whether measurement of bronchial hyperresponsiveness could be used to pred...

Resolution of Bronchial Hyperresponsiveness